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Optimizing the Decoding Probability and Coverage Ratio of Composite DNA

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This paper studies two problems that are motivated by the novel recent approach of composite DNA that takes advantage of the DNA synthesis property which generates a huge number of copies for every synthesized strand. Under this paradigm, every composite symbols does not store a single nucleotide but a mixture of the four DNA nucleotides. The first problem studies the expected number of strand reads in order to decode a composite strand or a group of composite strands.

Committee members 39355

Imperial College London
Department Electrical and Electronic Engineering
South Kensington Campus
SW7 2BT London, UK
 

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Committee members 39354

EE Department, Viterbi School of Engineering
University of Southern California
3740 McClintock Ave., EEB 528
Los Angeles, CA 90089
Tel: (213)740-4683
Fax: (213)740-8729